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Perchlorate
What is Perchlorate?
Perchlorate is both a naturally occurring and man-made chemical. Most of the perchlorate manufactured in the United States is used as the primary ingredient of solid rocket propellant. Wastes from the manufacture and improper disposal of perchlorate-containing chemicals are increasingly being discovered in soil and water.
Perchlorate interferes with iodide uptake into the thyroid gland. Because iodide is an essential component of thyroid hormones, perchlorate disrupts how the thyroid functions. In adults, the thyroid helps to regulate metabolism. In children, the thyroid plays a major role in proper development in addition to metabolism. Impairment of thyroid function in expectant mothers may impact the fetus and newborn and result in effects including changes in behavior, delayed development and decreased learning capability. Changes in thyroid hormone levels may also result in thyroid gland tumors. Perchlorate's disruption of iodide uptake is the key event leading to changes in development or tumor formation.
The assessment provides a hypothetical conversion of the draft RfD to a drinking water equivalent level (DWEL), assuming factors of 70 kilogram (kg) body weight and 2 liter (L) of water consumption per day. The converted draft estimate would be 1 microgram per liter (ug/L) or 1 part per billion (ppb). If the Agency were to make a determination to regulate perchlorate, the RfD along with other considerations would factor into the final value.
to learn more about perchlorate removal using Ion Exchange and Chromatagraphy Solutions.
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